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The Nuclear Receptor Coactivator Amplified in Breast Cancer-1 Is Required for Neu (ErbB2/HER2) Activation, Signaling, and Mammary Tumorigenesis in Mice

Overexpression of the oncogene amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) induces mammary tumorigenesis in mice. In breast cancer, high levels of AIB1/SRC-3 and the growth factor receptor HER2/neu predict resistance to endocrine therapy and poor outcome. However, a me...

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Detalhes bibliográficos
Main Authors:	Fereshteh, Mark P., Tilli, Maddalena T., Kim, Sung Eun, Xu, Jianming, O’Malley, Bert W., Wellstein, Anton, Furth, Priscilla A., Riegel, Anna T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	2008
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3641830/ https://ncbi.nlm.nih.gov/pubmed/18483252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6702
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