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Selective Roles of E2Fs for ErbB2- and Myc-mediated Mammary Tumorigenesis
Previous studies have demonstrated that cyclin D1, an upstream regulator of the Rb/E2F pathway, is an essential component of the ErbB2/Ras (but not the Wnt/Myc) oncogenic pathway in the mammary epithelium. However, the role of specific E2fs for ErbB2/Ras-mediated mammary tumorigenesis remains unknow...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4032808/ https://ncbi.nlm.nih.gov/pubmed/24276244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.511 |
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