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Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis
It has been argued that genetic instability is required to generate the myriad mutations that fuel tumor initiation and progression and, in fact, patients with heritable cancer susceptibility syndromes harbor defects in specific genes that normally maintain DNA integrity. However, the vast majority...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122599/ https://ncbi.nlm.nih.gov/pubmed/11867754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052710299 |
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