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Somatic Expression of PyMT or Activated ErbB2 Induces Estrogen-Independent Mammary Tumorigenesis

Estrogen signaling is required for the proliferation of normal breast epithelial cells. However, prophylactic inhibition of estrogen signaling fails to prevent 56% of human breast cancer cases. The underlying mechanism is not well understood. Aberrant activation of growth factor signaling is known t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Michael J. Toneff, Zhijun Du, Jie Dong, Jian Huang, Parisa Sinai, James Forman, Susan Hilsenbeck, Rachel Schiff, Shixia Huang, Yi Li
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2010-09-01
Cyfres:Neoplasia: An International Journal for Oncology Research
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S1476558610800739
Tagiau: Ychwanegu Tag
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