Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis

It has been argued that genetic instability is required to generate the myriad mutations that fuel tumor initiation and progression and, in fact, patients with heritable cancer susceptibility syndromes harbor defects in specific genes that normally maintain DNA integrity. However, the vast majority...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Liu, Shiquan, Liu, Wenjing, Jakubczak, John L., Erexson, Gregory L., Tindall, Kenneth R., Chan, Richard, Muller, William J., Adhya, Sankar, Garges, Susan, Merlino, Glenn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052710299
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