Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis

It has been argued that genetic instability is required to generate the myriad mutations that fuel tumor initiation and progression and, in fact, patients with heritable cancer susceptibility syndromes harbor defects in specific genes that normally maintain DNA integrity. However, the vast majority...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Liu, Shiquan, Liu, Wenjing, Jakubczak, John L., Erexson, Gregory L., Tindall, Kenneth R., Chan, Richard, Muller, William J., Adhya, Sankar, Garges, Susan, Merlino, Glenn
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052710299
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