Evaluation of C-ErbB-2 Overexpression and Her-2/neu Gene Copy Number Heterogeneity in Barrett’s Adenocarcinoma

Amplifiction of the Her-2/neu gene is accompanied by overexpression of its cell surface receptor product, c‐erbB‐2 protein. To investigate the degree of intratumoural heterogeneity we applied immunohistochemistry in primary Barrett’s adenocarcinoma (BCA) (n = 6) and dysplasia adjacent to the carcino...

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Detalhes bibliográficos
Publicado no:Anal Cell Pathol
Main Authors: Walch, Axel, Bink, Karin, Gais, Peter, Stangl, Stefan, Hutzler, Peter, Aubele, Michaela, Mueller, James, Höfler, Heinz, Werner, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615972/
https://ncbi.nlm.nih.gov/pubmed/11007435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2000/947249
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