The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis

BACKGROUND: Altered tumor cell metabolism is an emerging hallmark of cancer; however, the precise role for glucose in tumor initiation is not known. GLUT1 (SLC2A1) is expressed in breast cancer cells and is likely responsible for avid glucose uptake observed in established tumors. We have shown that...

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Publicat a:Breast Cancer Res
Autors principals: Wellberg, Elizabeth A., Johnson, Stevi, Finlay-Schultz, Jessica, Lewis, Andrew S., Terrell, Kristina L., Sartorius, Carol A., Abel, E. Dale, Muller, William J., Anderson, Steven M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168867/
https://ncbi.nlm.nih.gov/pubmed/27998284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0795-0
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