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The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis

BACKGROUND: Altered tumor cell metabolism is an emerging hallmark of cancer; however, the precise role for glucose in tumor initiation is not known. GLUT1 (SLC2A1) is expressed in breast cancer cells and is likely responsible for avid glucose uptake observed in established tumors. We have shown that...

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Bibliografische gegevens
Gepubliceerd in:Breast Cancer Res
Hoofdauteurs: Wellberg, Elizabeth A., Johnson, Stevi, Finlay-Schultz, Jessica, Lewis, Andrew S., Terrell, Kristina L., Sartorius, Carol A., Abel, E. Dale, Muller, William J., Anderson, Steven M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168867/
https://ncbi.nlm.nih.gov/pubmed/27998284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0795-0
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