The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis

BACKGROUND: Altered tumor cell metabolism is an emerging hallmark of cancer; however, the precise role for glucose in tumor initiation is not known. GLUT1 (SLC2A1) is expressed in breast cancer cells and is likely responsible for avid glucose uptake observed in established tumors. We have shown that...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res
Main Authors: Wellberg, Elizabeth A., Johnson, Stevi, Finlay-Schultz, Jessica, Lewis, Andrew S., Terrell, Kristina L., Sartorius, Carol A., Abel, E. Dale, Muller, William J., Anderson, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168867/
https://ncbi.nlm.nih.gov/pubmed/27998284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0795-0
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