The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis

BACKGROUND: Altered tumor cell metabolism is an emerging hallmark of cancer; however, the precise role for glucose in tumor initiation is not known. GLUT1 (SLC2A1) is expressed in breast cancer cells and is likely responsible for avid glucose uptake observed in established tumors. We have shown that...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Wellberg, Elizabeth A., Johnson, Stevi, Finlay-Schultz, Jessica, Lewis, Andrew S., Terrell, Kristina L., Sartorius, Carol A., Abel, E. Dale, Muller, William J., Anderson, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168867/
https://ncbi.nlm.nih.gov/pubmed/27998284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0795-0
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