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Amyloid precursor protein controls cholesterol turnover needed for neuronal activity
Perturbation of lipid metabolism favours progression of Alzheimer disease, in which processing of Amyloid Precursor Protein (APP) has important implications. APP cleavage is tightly regulated by cholesterol and APP fragments regulate lipid homeostasis. Here, we investigated whether up or down regula...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
WILEY-VCH Verlag
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628100/ https://ncbi.nlm.nih.gov/pubmed/23554170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202215 |
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