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Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

The amyloid precursor protein (APP) modulates synaptic activity, resulting from the fine tuning of excitatory and inhibitory neurotransmission. GABAergic inhibitory neurotransmission is affected by modifications in intracellular chloride concentrations regulated by Na(+)-K(+)-2Cl(−) cotransporter 1...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Doshina, Anna, Gourgue, Florian, Onizuka, Michiho, Opsomer, Remi, Wang, Peng, Ando, Kunie, Tasiaux, Bernadette, Dewachter, Ilse, Kienlen-Campard, Pascal, Brion, Jean-Pierre, Gailly, Philippe, Octave, Jean-Noël, Pierrot, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428293/
https://ncbi.nlm.nih.gov/pubmed/28337033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00325-2
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