Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

The amyloid precursor protein (APP) modulates synaptic activity, resulting from the fine tuning of excitatory and inhibitory neurotransmission. GABAergic inhibitory neurotransmission is affected by modifications in intracellular chloride concentrations regulated by Na(+)-K(+)-2Cl(−) cotransporter 1...

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Publicado en:Sci Rep
Autores principales: Doshina, Anna, Gourgue, Florian, Onizuka, Michiho, Opsomer, Remi, Wang, Peng, Ando, Kunie, Tasiaux, Bernadette, Dewachter, Ilse, Kienlen-Campard, Pascal, Brion, Jean-Pierre, Gailly, Philippe, Octave, Jean-Noël, Pierrot, Nathalie
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428293/
https://ncbi.nlm.nih.gov/pubmed/28337033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00325-2
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