Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release

The amyloid precursor protein (APP) has been extensively studied as the precursor of the β-amyloid (Aβ) peptide, the major component of the senile plaques found in the brain of Alzheimer’s disease (AD) patients. However, the function of APP per se in neuronal physiology remains to be fully elucidate...

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Vydáno v:eNeuro
Hlavní autoři: Opsomer, Rémi, Contino, Sabrina, Perrin, Florian, Gualdani, Roberta, Tasiaux, Bernadette, Doyen, Pierre, Vergouts, Maxime, Vrancx, Céline, Doshina, Anna, Pierrot, Nathalie, Octave, Jean-Noël, Gailly, Philippe, Stanga, Serena, Kienlen-Campard, Pascal
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2020
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Research Article: New Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262005/
https://ncbi.nlm.nih.gov/pubmed/32327470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0322-19.2020
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