Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release

The amyloid precursor protein (APP) has been extensively studied as the precursor of the β-amyloid (Aβ) peptide, the major component of the senile plaques found in the brain of Alzheimer’s disease (AD) patients. However, the function of APP per se in neuronal physiology remains to be fully elucidate...

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Publicado en:eNeuro
Autores principales: Opsomer, Rémi, Contino, Sabrina, Perrin, Florian, Gualdani, Roberta, Tasiaux, Bernadette, Doyen, Pierre, Vergouts, Maxime, Vrancx, Céline, Doshina, Anna, Pierrot, Nathalie, Octave, Jean-Noël, Gailly, Philippe, Stanga, Serena, Kienlen-Campard, Pascal
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262005/
https://ncbi.nlm.nih.gov/pubmed/32327470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0322-19.2020
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