Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release

The amyloid precursor protein (APP) has been extensively studied as the precursor of the β-amyloid (Aβ) peptide, the major component of the senile plaques found in the brain of Alzheimer’s disease (AD) patients. However, the function of APP per se in neuronal physiology remains to be fully elucidate...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eNeuro
Prif Awduron: Opsomer, Rémi, Contino, Sabrina, Perrin, Florian, Gualdani, Roberta, Tasiaux, Bernadette, Doyen, Pierre, Vergouts, Maxime, Vrancx, Céline, Doshina, Anna, Pierrot, Nathalie, Octave, Jean-Noël, Gailly, Philippe, Stanga, Serena, Kienlen-Campard, Pascal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2020
Pynciau:
Research Article: New Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262005/
https://ncbi.nlm.nih.gov/pubmed/32327470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0322-19.2020
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