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Sex-regulated gene dosage effect of PPARα on synaptic plasticity

Mechanisms driving cognitive improvements following nuclear receptor activation are poorly understood. The peroxisome proliferator–activated nuclear receptor alpha (PPARα) forms heterodimers with the nuclear retinoid X receptor (RXR). We report that PPARα mediates the improvement of hippocampal syna...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Pierrot, Nathalie, Ris, Laurence, Stancu, Ilie-Cosmin, Doshina, Anna, Ribeiro, Floriane, Tyteca, Donatienne, Baugé, Eric, Lalloyer, Fanny, Malong, Liza, Schakman, Olivier, Leroy, Karelle, Kienlen-Campard, Pascal, Gailly, Philippe, Brion, Jean-Pierre, Dewachter, Ilse, Staels, Bart, Octave, Jean-Noël
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427998/
https://ncbi.nlm.nih.gov/pubmed/30894406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800262
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