Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

Telomeres, the ends of linear eukaryotic chromosomes, shorten due to incomplete DNA replication and nucleolytic degradation. Cells counteract this shortening by employing a specialized reverse transcriptase called telomerase, which uses deoxyribonucleoside triphosphates (dNTPs) to extend telomeres....

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Autori principali: Gupta, Amitabha, Sharma, Sushma, Reichenbach, Patrick, Marjavaara, Lisette, Nilsson, Anna Karin, Lingner, Joachim, Chabes, Andrei, Rothstein, Rodney, Chang, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2013
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606089/
https://ncbi.nlm.nih.gov/pubmed/23335335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.149120
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