Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

Telomeres, the ends of linear eukaryotic chromosomes, shorten due to incomplete DNA replication and nucleolytic degradation. Cells counteract this shortening by employing a specialized reverse transcriptase called telomerase, which uses deoxyribonucleoside triphosphates (dNTPs) to extend telomeres....

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Bibliografische gegevens
Hoofdauteurs: Gupta, Amitabha, Sharma, Sushma, Reichenbach, Patrick, Marjavaara, Lisette, Nilsson, Anna Karin, Lingner, Joachim, Chabes, Andrei, Rothstein, Rodney, Chang, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2013
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Investigations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606089/
https://ncbi.nlm.nih.gov/pubmed/23335335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.149120
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