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Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint
A balanced supply of deoxyribonucleoside triphosphates (dNTPs) is one of the key prerequisites for faithful genome duplication. Both the overall concentration and the balance among the individual dNTPs (dATP, dTTP, dGTP, and dCTP) are tightly regulated, primarily by the enzyme ribonucleotide reducta...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896522/ https://ncbi.nlm.nih.gov/pubmed/20215435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq128 |
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