A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance

The balance and the overall concentration of intracellular deoxyribonucleoside triphosphates (dNTPs) are important determinants of faithful DNA replication. Despite the established fact that changes in dNTP pools negatively influence DNA replication fidelity, it is not clear why certain dNTP pool al...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Schmidt, Tobias T, Sharma, Sushma, Reyes, Gloria X, Gries, Kerstin, Gross, Maike, Zhao, Boyu, Yuan, Jui-Hung, Wade, Rebecca, Chabes, Andrei, Hombauer, Hans
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Genome Integrity, Repair and Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326808/
https://ncbi.nlm.nih.gov/pubmed/30462295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1154
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍