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Ixr1 Is Required for the Expression of the Ribonucleotide Reductase Rnr1 and Maintenance of dNTP Pools

The Saccharomyces cerevisiae Dun1 protein kinase is a downstream target of the conserved Mec1-Rad53 checkpoint pathway. Dun1 regulates dNTP pools during an unperturbed cell cycle and after DNA damage by modulating the activity of ribonucleotide reductase (RNR) by multiple mechanisms, including phosp...

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Detalhes bibliográficos
Main Authors: Tsaponina, Olga, Barsoum, Emad, Åström, Stefan U., Chabes, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088718/
https://ncbi.nlm.nih.gov/pubmed/21573136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002061
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