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dNTP pools determine fork progression and origin usage under replication stress

Intracellular deoxyribonucleoside triphosphate (dNTP) pools must be tightly regulated to preserve genome integrity. Indeed, alterations in dNTP pools are associated with increased mutagenesis, genomic instability and tumourigenesis. However, the mechanisms by which altered or imbalanced dNTP pools a...

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書誌詳細
主要な著者: Poli, Jérôme, Tsaponina, Olga, Crabbé, Laure, Keszthelyi, Andrea, Pantesco, Véronique, Chabes, Andrei, Lengronne, Armelle, Pasero, Philippe
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280562/
https://ncbi.nlm.nih.gov/pubmed/22234185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.470
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