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Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools
Telomeres, the ends of linear eukaryotic chromosomes, shorten due to incomplete DNA replication and nucleolytic degradation. Cells counteract this shortening by employing a specialized reverse transcriptase called telomerase, which uses deoxyribonucleoside triphosphates (dNTPs) to extend telomeres....
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Genetics Society of America
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606089/ https://ncbi.nlm.nih.gov/pubmed/23335335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.149120 |
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