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The roles of sphingosine kinase 1 and 2 in regulating the Warburg effect in prostate cancer cells
Two isoforms of sphingosine kinase, SK1 and SK2, catalyze the formation of the bioactive lipid sphingosine 1-phosphate (S1P) in mammalian cells. We have previously shown that treatment of androgen-sensitive LNCaP prostate cancer cells with a non-selective SK isoform inhibitor, 2-(p-hydroxyanilino)-...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595369/ https://ncbi.nlm.nih.gov/pubmed/23314175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.01.002 |
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