A carregar...
Synthesis of selective inhibitors of sphingosine kinase 1
Sphingosine kinase isoform 1 (SK1) inhibitors may serve as therapeutic agents for proliferative diseases, including hypertension. We synthesized a series of sphingosine-based SK1-selective inhibitors, the most potent of which is RB-005 (IC(50) = 3.6 µM), which also induced proteasomal degradation of...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608193/ https://ncbi.nlm.nih.gov/pubmed/23388656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc00181d |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|