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SPHINGOSINE KINASE INHIBITORS AND CANCER: SEEKING THE GOLDEN SWORD OF HERCULES

There is considerable evidence that sphingosine kinases play a key role in cancer progression, which might involve positive selection of cancer cells that have been provided with a survival and growth advantage as a consequence of over-expression of the enzyme. Therefore, inhibitors of sphingosine k...

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Detalhes bibliográficos
Main Authors: Pyne, Susan, Bittman, Robert, Pyne, Nigel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206172/
https://ncbi.nlm.nih.gov/pubmed/21940750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2364
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