Spirocyclic replacements for the isatin in the highly selective, muscarinic M(1) PAM ML137: the continued optimization of an MLPCN probe molecule

Lignende værker

• Isatin replacements applied to the highly selective, muscarinic M(1) PAM ML137: Continued optimization of an MLPCN probe molecule
  af: Melancon, Bruce J., et al.
  Udgivet: (2012)
• Continued optimization of the MLPCN probe ML071 into highly potent agonists of the hM(1) muscarinic acetylcholine receptor
  af: Melancon, Bruce J., et al.
  Udgivet: (2012)
• Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012
  af: Melancon, Bruce J., et al.
  Udgivet: (2012)
• Discovery and optimization of a novel, selective and brain penetrant M(1) positive allosteric modulator (PAM): the development of ML169, an MLPCN Probe
  af: Reid, Paul R., et al.
  Udgivet: (2010)
• Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012
  af: Melancon, Bruce J., et al.
  Udgivet: (2011)