The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair

CtIP plays an important role in homologous recombination (HR)–mediated DNA double-stranded break (DSB) repair and interacts with Nbs1 and BRCA1, which are linked to Nijmegen breakage syndrome (NBS) and familial breast cancer, respectively. We identified new CDK phosphorylation sites on CtIP and foun...

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Autors principals: Wang, Hailong, Shi, Linda Z., Wong, Catherine C. L., Han, Xuemei, Hwang, Patty Yi-Hwa, Truong, Lan N., Zhu, Qingyuan, Shao, Zhengping, Chen, David J., Berns, Michael W., Yates, John R., Chen, Longchuan, Wu, Xiaohua
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585124/
https://ncbi.nlm.nih.gov/pubmed/23468639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003277
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