The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair

CtIP plays an important role in homologous recombination (HR)–mediated DNA double-stranded break (DSB) repair and interacts with Nbs1 and BRCA1, which are linked to Nijmegen breakage syndrome (NBS) and familial breast cancer, respectively. We identified new CDK phosphorylation sites on CtIP and foun...

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Autores principales: Wang, Hailong, Shi, Linda Z., Wong, Catherine C. L., Han, Xuemei, Hwang, Patty Yi-Hwa, Truong, Lan N., Zhu, Qingyuan, Shao, Zhengping, Chen, David J., Berns, Michael W., Yates, John R., Chen, Longchuan, Wu, Xiaohua
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585124/
https://ncbi.nlm.nih.gov/pubmed/23468639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003277
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