The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair

CtIP plays an important role in homologous recombination (HR)–mediated DNA double-stranded break (DSB) repair and interacts with Nbs1 and BRCA1, which are linked to Nijmegen breakage syndrome (NBS) and familial breast cancer, respectively. We identified new CDK phosphorylation sites on CtIP and foun...

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Detalhes bibliográficos
Main Authors: Wang, Hailong, Shi, Linda Z., Wong, Catherine C. L., Han, Xuemei, Hwang, Patty Yi-Hwa, Truong, Lan N., Zhu, Qingyuan, Shao, Zhengping, Chen, David J., Berns, Michael W., Yates, John R., Chen, Longchuan, Wu, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585124/
https://ncbi.nlm.nih.gov/pubmed/23468639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003277
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