The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair

CtIP plays an important role in homologous recombination (HR)–mediated DNA double-stranded break (DSB) repair and interacts with Nbs1 and BRCA1, which are linked to Nijmegen breakage syndrome (NBS) and familial breast cancer, respectively. We identified new CDK phosphorylation sites on CtIP and foun...

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Κύριοι συγγραφείς: Wang, Hailong, Shi, Linda Z., Wong, Catherine C. L., Han, Xuemei, Hwang, Patty Yi-Hwa, Truong, Lan N., Zhu, Qingyuan, Shao, Zhengping, Chen, David J., Berns, Michael W., Yates, John R., Chen, Longchuan, Wu, Xiaohua
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585124/
https://ncbi.nlm.nih.gov/pubmed/23468639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003277
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