Caricamento...
A New Model for Allosteric Regulation of Phenylalanine Hydroxylase: Implications for Disease and Therapeutics
The structural basis for allosteric regulation of phenylalanine hydroxylase (PAH), whose dysfunction causes phenylketonuria (PKU), is poorly understood. A new morpheein model for PAH allostery is proposed to consist of a dissociative equilibrium between two architecturally different tetramers whose...
Salvato in:
| Autori principali: | , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580015/ https://ncbi.nlm.nih.gov/pubmed/23296088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.12.017 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|