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Identification of the Allosteric Site for Phenylalanine in Rat Phenylalanine Hydroxylase

Liver phenylalanine hydroxylase (PheH) is an allosteric enzyme that requires activation by phenylalanine for full activity. The location of the allosteric site for phenylalanine has not been established. NMR spectroscopy of the isolated regulatory domain (RDPheH(25–117) is the regulatory domain of P...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Zhang, Shengnan, Fitzpatrick, Paul F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817173/
https://ncbi.nlm.nih.gov/pubmed/26823465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709998
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