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Identification of the Allosteric Site for Phenylalanine in Rat Phenylalanine Hydroxylase
Liver phenylalanine hydroxylase (PheH) is an allosteric enzyme that requires activation by phenylalanine for full activity. The location of the allosteric site for phenylalanine has not been established. NMR spectroscopy of the isolated regulatory domain (RDPheH(25–117) is the regulatory domain of P...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817173/ https://ncbi.nlm.nih.gov/pubmed/26823465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709998 |
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