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Allosteric Regulation of Phenylalanine Hydroxylase
The liver enzyme phenylalanine hydroxylase is responsible for conversion of excess phenylalanine in the diet to tyrosine. Phenylalanine hydroxylase is activated by phenylalanine; this activation is inhibited by the physiological reducing substrate tetrahydrobiopterin. Phosphorylation of Ser16 lowers...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271142/ https://ncbi.nlm.nih.gov/pubmed/22005392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.09.012 |
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