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Allosteric Regulation of Phenylalanine Hydroxylase

The liver enzyme phenylalanine hydroxylase is responsible for conversion of excess phenylalanine in the diet to tyrosine. Phenylalanine hydroxylase is activated by phenylalanine; this activation is inhibited by the physiological reducing substrate tetrahydrobiopterin. Phosphorylation of Ser16 lowers...

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Bibliografiska uppgifter
Huvudupphovsman: Fitzpatrick, Paul F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271142/
https://ncbi.nlm.nih.gov/pubmed/22005392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.09.012
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