Mechanism of Aromatic Amino Acid Hydroxylation

Por Fitzpatrick, Paul F.
Publicado em 2003

Insights into the mechanisms of flavoprotein oxidases from kinetic isotope effects

Por FITZPATRICK, PAUL F.
Publicado em 2007

Oxidation of Amines by Flavoproteins

Por Fitzpatrick, Paul F.
Publicado em 2009

Allosteric Regulation of Phenylalanine Hydroxylase

Por Fitzpatrick, Paul F.
Publicado em 2011

Combining Solvent Isotope Effects with Substrate Isotope Effects in Mechanistic Studies of Alcohol and Amine Oxidation by Enzymes

Por Fitzpatrick, Paul F.
Publicado no Biochim Biophys Acta (2014)

Structural insights into the regulation of aromatic amino acid hydroxylation

Por Fitzpatrick, Paul F.
Publicado no Curr Opin Struct Biol (2015)

Identification of Tyr413 as an Active Site Residue in the Flavoprotein Tryptophan 2-Monooxygenase and Analysis of Its Contribution to Catalysis

Por Sobrado, Pablo, Fitzpatrick, Paul F.
Publicado em 2003

Solvent and Primary Deuterium Isotope Effects Show That Lactate CH and OH Bond Cleavages Are Concerted in Y254F Flavocytochrome b(2), Consistent with a Hydride Transfer Mechanism

Por Sobrado, Pablo, Fitzpatrick, Paul F.
Publicado em 2003

Analysis of the Role of the Active Site Residue Arg98 in the Flavoprotein Tryptophan 2-Monooxygenase, a Member of the l-Amino Oxidase Family

Por Sobrado, Pablo, Fitzpatrick, Paul F.
Publicado em 2003

Mechanistic Studies of Mouse Polyamine Oxidase with N1,N12-Bisethylspermine as a Substrate

Por Royo, Montserrat, Fitzpatrick, Paul F.
Publicado em 2005

Characterization of Metal Ligand Mutants of Phenylalanine Hydroxylase: Insights into the Plasticity of a 2-Histidine-1-Carboxylate Triad

Por Li, Jun, Fitzpatrick, Paul F.
Publicado em 2008

The synthesis of deuterium-labeled spermine, N(1)-acetylspermine and N(1)-acetylspermidine

Por Gawandi, Vijay, Fitzpatrick, Paul F.
Publicado em 2007

Structures and Mechanism of the Monoamine Oxidase Family

Por Gaweska, Helena, Fitzpatrick, Paul F.
Publicado em 2011

Regulation of Phenylalanine Hydroxylase: Conformational Changes Upon Phosphorylation Detected by H/D Exchange and Mass Spectrometry

Por Li, Jun, Fitzpatrick, Paul F.
Publicado em 2013

Solvent Isotope and Viscosity Effects on the Steady-State Kinetics of the Flavoprotein Nitroalkane Oxidase

Por Gadda, Giovanni, Fitzpatrick, Paul F.
Publicado em 2013

Identification of the Allosteric Site for Phenylalanine in Rat Phenylalanine Hydroxylase

Por Zhang, Shengnan, Fitzpatrick, Paul F.
Publicado no J Biol Chem (2016)

Intrinsic Isotope Effects on Benzylic Hydroxylation by the Aromatic Amino Acid Hydroxylases: Evidence for Hydrogen Tunneling, Coupled Motion, and Similar Reactivities

Por Pavon, Jorge Alex, Fitzpatrick, Paul F.
Publicado em 2005

Reductive Half-Reaction of Nitroalkane Oxidase: Effect of Mutation of the Active Site Aspartate to Glutamate ,

Por Valley, Michael P., Fitzpatrick, Paul F.
Publicado em 2003

pH and Kinetic Isotope Effects on Sarcosine Oxidation by N-Methyltryptophan Oxidase

Por Ralph, Erik C., Fitzpatrick, Paul F.
Publicado em 2005

Comparison of Enzymatic and Non-Enzymatic Nitroethane Anion Formation: Thermodynamics and Contribution of Tunneling

Por Valley, Michael P., Fitzpatrick, Paul F.
Publicado em 2004