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pH and Kinetic Isotope Effects on Sarcosine Oxidation by N-Methyltryptophan Oxidase

N-Methyltryptophan oxidase (MTOX), a flavoenzyme from Escherichia coli, catalyzes the oxidative demethylation of secondary amino acids such as N-methyltryptophan or N-methylglycine (sarcosine). MTOX is one of several flavin-dependent amine oxidases whose chemical mechanism is still debated. The kine...

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Detalhes bibliográficos
Main Authors: Ralph, Erik C., Fitzpatrick, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752209/
https://ncbi.nlm.nih.gov/pubmed/15723552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi047716h
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