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pH and Kinetic Isotope Effects on Sarcosine Oxidation by N-Methyltryptophan Oxidase

N-Methyltryptophan oxidase (MTOX), a flavoenzyme from Escherichia coli, catalyzes the oxidative demethylation of secondary amino acids such as N-methyltryptophan or N-methylglycine (sarcosine). MTOX is one of several flavin-dependent amine oxidases whose chemical mechanism is still debated. The kine...

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Hlavní autoři: Ralph, Erik C., Fitzpatrick, Paul F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752209/
https://ncbi.nlm.nih.gov/pubmed/15723552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi047716h
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