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Mechanistic Studies of the Yeast Polyamine Oxidase Fms1: Kinetic Mechanism, Substrate Specificity, and pH Dependence

The flavoprotein oxidase Fms1 from Saccharomyces cerevisiae catalyzes the oxidation of spermine and N(1)-acetylspermine to yield spermidine and 3-aminopropanal or N-acetyl-3-aminopropanal. The kinetic mechanism of the enzyme has been determined with both substrates. The initial velocity patterns are...

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Main Authors: Adachi, Mariya S., Torres, Jason M., Fitzpatrick, Paul F.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999662/
https://ncbi.nlm.nih.gov/pubmed/21067138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1016099
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