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Direct Evidence for a Phenylalanine Site in the Regulatory Domain of Phenylalanine Hydroxylase
The hydroxylation of phenylalanine to tyrosine by the liver enzyme phenylalanine hydroxylase is regulated by the level of phenylalanine. Whether there is a distinct allosteric binding site for phenylalanine outside of the active site has been unclear. The enzyme contains an N-terminal regulatory dom...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019263/ https://ncbi.nlm.nih.gov/pubmed/20951114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.10.009 |
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