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Direct Evidence for a Phenylalanine Site in the Regulatory Domain of Phenylalanine Hydroxylase

The hydroxylation of phenylalanine to tyrosine by the liver enzyme phenylalanine hydroxylase is regulated by the level of phenylalanine. Whether there is a distinct allosteric binding site for phenylalanine outside of the active site has been unclear. The enzyme contains an N-terminal regulatory dom...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Li, Jun, Ilangovan, Udayar, Daubner, S. Colette, Hinck, Andrew P., Fitzpatrick, Paul F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019263/
https://ncbi.nlm.nih.gov/pubmed/20951114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.10.009
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