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Direct Evidence for a Phenylalanine Site in the Regulatory Domain of Phenylalanine Hydroxylase

The hydroxylation of phenylalanine to tyrosine by the liver enzyme phenylalanine hydroxylase is regulated by the level of phenylalanine. Whether there is a distinct allosteric binding site for phenylalanine outside of the active site has been unclear. The enzyme contains an N-terminal regulatory dom...

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Sonraí Bibleagrafaíochta
Main Authors: Li, Jun, Ilangovan, Udayar, Daubner, S. Colette, Hinck, Andrew P., Fitzpatrick, Paul F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019263/
https://ncbi.nlm.nih.gov/pubmed/20951114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.10.009
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