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Dynamic Regulation of Phenylalanine Hydroxylase by Simulated Redox Manipulation

Recent clinical studies revealed increased phenylalanine levels and phenylalanine to tyrosine ratios in patients suffering from infection, inflammation and general immune activity. These data implicated down-regulation of activity of phenylalanine hydroxylase by oxidative stress upon in vivo immune...

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Detalhes bibliográficos
Main Authors: Fuchs, Julian E., Huber, Roland G., von Grafenstein, Susanne, Wallnoefer, Hannes G., Spitzer, Gudrun M., Fuchs, Dietmar, Liedl, Klaus R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534100/
https://ncbi.nlm.nih.gov/pubmed/23300845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053005
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