Modulation of Gamma-Secretase for the Treatment of Alzheimer's Disease

The Amyloid Hypothesis states that the cascade of events associated with Alzheimer's disease (AD)—formation of amyloid plaques, neurofibrillary tangles, synaptic loss, neurodegeneration, and cognitive decline—are triggered by Aβ peptide dysregulation (Kakuda et al., 2006, Sato et al., 2003, Qi-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tate, Barbara, McKee, Timothy D., Loureiro, Robyn M. B., Dumin, Jo Ann, Xia, Weiming, Pojasek, Kevin, Austin, Wesley F., Fuller, Nathan O., Hubbs, Jed L., Shen, Ruichao, Jonker, Jeff, Ives, Jeff, Bronk, Brian S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536039/
https://ncbi.nlm.nih.gov/pubmed/23320246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/210756
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