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Efficacy of SPI-1865, a novel gamma-secretase modulator, in multiple rodent models
INTRODUCTION: Modulation of the gamma-secretase enzyme, which reduces the production of the amyloidogenic Aβ(42 )peptide while sparing the production of other Aβ species, is a promising therapeutic approach for the treatment of Alzheimer's disease. Satori has identified a unique class of small...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707052/ https://ncbi.nlm.nih.gov/pubmed/23597079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt173 |
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