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Natural Product and Natural Product-Derived Gamma Secretase Modulators from Actaea Racemosa Extracts

Alzheimer’s disease is characterized by pathogenic oligomerization, aggregation, and deposition of amyloid beta peptide (Aβ), resulting in severe neuronal toxicity and associated cognitive dysfunction. In particular, increases in the absolute or relative level of the major long form of Aβ, Aβ42, are...

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Dades bibliogràfiques
Publicat a:Medicines (Basel)
Autors principals: Findeis, Mark A., Schroeder, Frank C., Creaser, Steffen P., McKee, Timothy D., Xia, Weiming
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456218/
https://ncbi.nlm.nih.gov/pubmed/28930205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicines2030127
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