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Natural Product and Natural Product-Derived Gamma Secretase Modulators from Actaea Racemosa Extracts

Alzheimer’s disease is characterized by pathogenic oligomerization, aggregation, and deposition of amyloid beta peptide (Aβ), resulting in severe neuronal toxicity and associated cognitive dysfunction. In particular, increases in the absolute or relative level of the major long form of Aβ, Aβ42, are...

詳細記述

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書誌詳細
出版年:Medicines (Basel)
主要な著者: Findeis, Mark A., Schroeder, Frank C., Creaser, Steffen P., McKee, Timothy D., Xia, Weiming
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456218/
https://ncbi.nlm.nih.gov/pubmed/28930205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicines2030127
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