Ładuje się......
Initial Optimization of a New Series of γ-Secretase Modulators Derived from a Triterpene Glycoside
[Image: see text] The discovery of a new series of γ-secretase modulators is disclosed. Starting from a triterpene glycoside γ-secretase modulator that gave a very low brain-to-plasma ratio, initial SAR and optimization involved replacement of a pendant sugar with a series of morpholines. This modif...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American
Chemical Society
2012
|
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025870/ https://ncbi.nlm.nih.gov/pubmed/24900406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300256p |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|