Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

Selection of aptamers from nucleic acid libraries by in vitro evolution represents a powerful method of identifying high-affinity ligands for a broad range of molecular targets. Nevertheless, a sizeable fraction of proteins remain difficult targets due to inherently limited chemical diversity of nuc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Davies, Douglas R., Gelinas, Amy D., Zhang, Chi, Rohloff, John C., Carter, Jeffrey D., O’Connell, Daniel, Waugh, Sheela M., Wolk, Steven K., Mayfield, Wesley S., Burgin, Alex B., Edwards, Thomas E., Stewart, Lance J., Gold, Larry, Janjic, Nebojsa, Jarvis, Thale C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523867/
https://ncbi.nlm.nih.gov/pubmed/23139410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213933109
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak