Modified nucleotides may have enhanced early RNA catalysis

The modern version of the RNA World Hypothesis begins with activated ribonucleotides condensing (nonenzymatically) to make RNA molecules, some of which possess (perhaps slight) catalytic activity. We propose that noncanonical ribonucleotides, which would have been inevitable under prebiotic conditio...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Wolk, Steven K., Mayfield, Wesley S., Gelinas, Amy D., Astling, David, Guillot, Jessica, Brody, Edward N., Janjic, Nebojsa, Gold, Larry
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2020
Gaiak:
Perspective
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165471/
https://ncbi.nlm.nih.gov/pubmed/32229566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809041117
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