Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor

Por Gupta, Shashi, Hirota, Masao, Waugh, Sheela M., Murakami, Ikuo, Suzuki, Tomoki, Muraguchi, Masahiro, Shibamori, Masafumi, Ishikawa, Yuichi, Jarvis, Thale C., Carter, Jeffrey D., Zhang, Chi, Gawande, Bharat, Vrkljan, Michael, Janjic, Nebojsa, Schneider, Daniel J.
Publicado em 2014

Pharmacokinetic Properties of DNA Aptamers with Base Modifications

Por Gupta, Shashi, Drolet, Daniel W., Wolk, Steven K., Waugh, Sheela M., Rohloff, John C., Carter, Jeffery D., Mayfield, Wesley S., Otis, Matthew R., Fowler, Catherine R., Suzuki, Tomoki, Hirota, Masao, Ishikawa, Yuichi, Schneider, Daniel J., Janjic, Nebojsa
Publicado no Nucleic Acid Ther (2017)

Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

Por Davies, Douglas R., Gelinas, Amy D., Zhang, Chi, Rohloff, John C., Carter, Jeffrey D., O’Connell, Daniel, Waugh, Sheela M., Wolk, Steven K., Mayfield, Wesley S., Burgin, Alex B., Edwards, Thomas E., Stewart, Lance J., Gold, Larry, Janjic, Nebojsa, Jarvis, Thale C.
Publicado em 2012